MiCARA - Microbiome Confounder-Adjusted Robust Analysis

Provides a comprehensive framework for multi-cohort microbiome differential abundance and residual correlation analysis. It integrates confounder-adjusted linear models with centered log-ratio transformed taxonomic and functional pathway profiles. The package features robust preprocessing, automated covariate handling, multiple-testing correction, and quality control diagnostics for multi-omics data. Interactive visualization tools are included to facilitate downstream interpretation of cross-domain interaction networks.